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Abstract
Radiotherapy planning is a crucial task in cancer patients’ management. This task is, however, very time consuming and prone to a high intra and inter subject variance and human errors. In this way, the present line of work aims at developing a tool to help the specialists in this task. The developed tool will consider the delimitation of anatomical regions of interest, since it is crucial to identify the organs at risk and minimize the exposure of these organs to the radiation. This paper, in particular, presents a lung segmentation algorithm, based on image processing techniques, such as intensity projection and region growing, for Computed Tomography volumes. Our pipeline consists in first separating two halves of the volume to isolate each lung. Then, three techniques for seed placement are developed. Finally, a traditional region growing algorithm has been changed in order to automatically derive the value of the threshold parameter. The results obtained for the three different techniques for seed placement were, respectively, 74%, 74% and 92% of DICE with the Iterative Region Growing algorithm. Although the presented results have as use case the Hodgkin Lymphoma, we believe that the developed method is generalizable to any other pathology. © 2019, Springer Nature Switzerland AG.

Abstract
The integration of functional imaging modality provided by Positron Emission Tomography (PET) and associated anatomical imaging modality provided by Computed Tomography (CT) has become an essential procedure both in the evaluation of different types of malignancy and in radiotherapy planning. The alignment of these two exams is thus of great importance. In this research work, three registration approaches (1) intensity-based registration, (2) rigid translation followed by intensity-based registration and (3) coarse registration followed by fine-tuning were evaluated and compared. To characterize the performance of these methods, 161 real volume scans from patients involved in Hodgkin Lymphoma staging were used: CT volumes used for radiotherapy planning were registered with PET volumes before any treatment. Registration results achieved 78%, 60%, and 91% of accuracy for methods (1), (2) and (3), respectively. Registration methods validation was extended to a corresponding landmarks points distance calculation. Methods (1), (2) and (3) achieved a median improvement registration rate of 66% mm, 51% mm and 70% mm, respectively. The accuracy of the proposed methods was further confirmed by extending our experiments to other multimodal datasets and in a monomodal dataset with different acquisition conditions. © 2018, Springer Nature Switzerland AG.

Abstract
Energy smart grids and other modern industrial control systems networks impose considerable security management challenges due to several factors: their broad geographic dispersion and capillarity, the constrained nature of many of the devices and network links that integrate them, and the fact that they are often fragmented across multiple domains, owned and managed by different entities which often have non-aligned or even competing interests. Due to this scenario, we propose to improve federated learning-based anomaly detection for smart grids and other industrial control networks, using a federated data-centric methodology that attends to the balance and causality of the data, improving the representation of the different classes of anomalies of the ingested data, which directly impact the classifier's performance. The proposed approach shows up to 33% performance improvements in terms of F1-score for attack classification, compared to the baseline federated approach (not attending to class imbalance and causality) on a broad range of industrial control systems traffic datasets.

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Abstract