Abstract
Tackling uncertainty is becoming increasingly relevant for decision-support across fields due to its critical impact on real-world problems. Uncertainty is often modelled using scenarios, which are combinations of possible outcomes of the uncertain parameters in a problem. Alongside expected value methods, decisions under uncertainty may also be tackled using methods that do not rely on probability distributions and model different decision-maker risk profiles. Scenarios are at the core of these approaches. Therefore, we propose a scenario generation methodology that seizes the structure and concepts of genetic algorithms. This methodology aims to obtain a diverse set of scenarios, evolving a scenario population with a diversity goal. Diversity is here expressed as the difference in the impact that scenarios have on the value of potential solutions to the problem. Moreover, this method does not require a priori knowledge of probability distributions or statistical moments of uncertain parameters, as it is based on their range. We adapt the available code for Biased-Random Key Genetic Algorithms to apply the methodology to a packing problem under demand uncertainty as a proof of concept, also extending its use to a multiobjective setting. We make available these code adaptations to allow the straightforward application of this scenario generation method to other problems. With this, the decision-maker obtains scenarios with a distinct impact on potential solutions, enabling the use of different criteria based on their profile and preferences.

Abstract
This paper proposes an innovative framework based on optimisation techniques that can support decision-making in water services. The proposed models estimate a Best-Practice frontier recurring to a ‘Benefit-of-the-Doubt’ formulation that enables benchmarking performance across decision-making units. We propose an innovative estimation of a pseudo-Malmquist index to compare the performance of groups. The framework’s relevance is illustrated using data of the Brazilian water and sanitation regulator, collected at the municipality level for the year 2019. The groups compared correspond to three Brazilian macro-regions. The results obtained show that the Southeast exhibits the best overall performance. The Northeast has a few municipalities with the best practices at a national level, but this macro-region has significant heterogeneity in performance levels. The South has a more homogeneous performance, but the best-performing municipalities in this macro-region are still far from Brazil’s best practices. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.

Abstract
This paper explores robust unconditional and conditional nonparametric approaches to support performance evaluation in problematic samples. Real-world assessments often face critical problems regarding available data, as samples may be relatively small, with high variability in the magnitude of the observed indicators and contextual conditions. This paper explores the possibility of mitigating the impact of potential outlier observations and variability in small samples using a robust nonparametric approach. This approach has the advantage of avoiding unnecessary loss of relevant information, retaining all the decision-making units of the original sample. We devote particular attention to identifying peers and targets in the robust nonparametric approach to guide improvements for underperforming units. The results are compared with a traditional deterministic approach to highlight the proposed method's benefits for problematic samples. This framework's applicability in internal benchmarking studies is illustrated with a case study within the wastewater treatment industry in Portugal.

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Abstract
Technological evolution has continuously driven the development of industries and consequently of society. The fourth industrial revolution consists in the combination of a set of physical and digital technologies that has been changing systems' operations within industries. The pharmaceutical industry has a considerable impact on well-being and has been strongly challenged with this new reality, not only by those that are transversal to all industries but also due to the fact that it is a highly regulated sector, which creates additional barriers for industry 4.0 (I4.0) initiative's implementation. However, it is due to the fact that this revolution provides high growth opportunities to the industry, and consequently for the improvement of population's quality of life, that this topic has been subject to so much research at a global level. This study's main purpose is to understand the impact of I4.0 paradigm implementation in the pharmaceutical industry (mainly in the production area), to analyze the technological readiness of Portuguese pharmaceutical companies to implement I4.0 technologies and to understand the role of the I4.0 paradigm to fight the pandemic situation caused by the COVID-19. To achieve this purpose, an exploratory multiple-case study based on semi-structured interviews was conducted in two Portuguese pharmaceutical companies. It is expected that the results of this work lead to recommendations that help the Portuguese pharmaceutical industry to be better prepared to face the challenges that are coming with this revolution.

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