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Publicações

Publicações por Daniela Santos

2025

Automating Data Extraction from PDF Sleep Reports Using Data Mining Techniques

Autores
Teixeira, F; Costa, J; Amorim, P; Guimarães, N; Ferreira Santos, D;

Publicação
Studies in health technology and informatics

Abstract
This work introduces a web application for extracting, processing, and visualizing data from sleep studies reports. Using Optical Character Recognition (OCR) and Natural Language Processing (NLP), the pipeline extracts over 75 key data points from four types of sleep reports. The web application offers an intuitive interface to view individual reports' details and aggregate data from multiple reports. The pipeline demonstrated 100% accuracy in extracting targeted information from a test set of 40 reports, even in cases with missing data or formatting inconsistencies. The developed tool streamlines the analysis of OSA reports, reducing the need for technical expertise and enabling healthcare providers and researchers to utilize sleep study data efficiently. Future work aims to expand the dataset for more complex analyses and imputation techniques.

2025

Clinical Annotation and Medical Image Anonymization for AI Model Training in Lung Cancer Detection

Autores
Freire, AM; Rodrigues, EM; Sousa, JV; Gouveia, M; Ferreira-Santos, D; Pereira, T; Oliveira, HP; Sousa, P; Silva, AC; Fernandes, MS; Hespanhol, V; Araújo, J;

Publicação
UNIVERSAL ACCESS IN HUMAN-COMPUTER INTERACTION, UAHCI 2025, PT I

Abstract
Lung cancer remains one of the most common and lethal forms of cancer, with approximately 1.8 million deaths annually, often diagnosed at advanced stages. Early detection is crucial, but it depends on physicians' accurate interpretation of computed tomography (CT) scans, a process susceptible to human limitations and variability. ByMe has developed a medical image annotation and anonymization tool designed to address these challenges through a human-centered approach. The tool enables physicians to seamlessly add structured attribute-based annotations (e.g., size, location, morphology) directly within their established workflows, ensuring intuitive interaction.Integrated with Picture Archiving and Communication Systems (PACS), the tool streamlines the annotation process and enhances usability by offering a dedicated worklist for retrospective and prospective case analysis. Robust anonymization features ensure compliance with privacy regulations such as the General Data Protection Regulation (GDPR), enabling secure dataset sharing for research and developing artificial intelligence (AI) models. Designed to empower AI integration, the tool not only facilitates the creation of high-quality datasets but also lays the foundation for incorporating AI-driven insights directly into clinical workflows. Focusing on usability, workflow integration, and privacy, this innovation bridges the gap between precision medicine and advanced technology. By providing the means to develop and train AI models for lung cancer detection, it holds the potential to significantly accelerate diagnosis as well as enhance its accuracy and consistency.

2024

The Utility of the IWGDF Diabetes-Related Foot Ulcer Risk Classification Annual Reassessment in the Primary Care Setting – a Cohort Study

Autores
Monteiro-Soares, M; Dores, J; Alves Palma, C; Galrito, S; Ferreira-Santos, D;

Publicação

Abstract
Background: We assessed the pertinence of yearly updating the International Working Group on the Diabetic Foot (IWGDF) risk classification in people with diabetes by quantifying the changes in the risk group and its accuracy in identifying those developing an ulcer (DFU) in a primary care setting. Methods: In our retrospective cohort study, we included all people with diabetes with a foot as-sessment registry between January 2016 and December 2018 in the Baixo Alentejo Local Health Unit. Foot-related data was collected at baseline after one and two years. DFU and/or death until December 2019 were registered. The proportion of people changing their risk status each year was calculated. Accuracy measures of the IWGDF classification to predict DFU occurrence at one, two, and three years were calculated. Results: A total of 2097 people were followed for three years, during which 0.1% died, and 12.4% developed a DFU. After two years, 3.6% of the participants had progressed to a higher-risk group. The IWGDF classification presented specificity values superior to 90% and negative predictive values superior to 99%. Conclusion: Foot risk status can be safely updated every two years instead of yearly. The IWGDF classification can accurately identify those not at risk of DFU.

2020

Prospective validation of a Bayesian network model in the diagnosis of Obstructive Sleep Apnea: preliminary results

Autores
Amorim, P; Ferreira Santos, D; Drummond, M; Rodrigues, PP;

Publicação
EUROPEAN RESPIRATORY JOURNAL

Abstract

2024

A new automated method to define clinically relevant pediatric sleep apnea phenotype

Autores
Camacho, KMC; Gomez-Pilar, J; Pereira-Rodrigues, P; Ferreira-Santos, D; Durante, CB; Albi, TR; Alvarez, DG; Gozal, D; Gutiérrez-Tobal, GC; Hornero, R; Del Campo, F;

Publicação
EUROPEAN RESPIRATORY JOURNAL

Abstract

2024

Prospective Validation and Usability Evaluation of a Mobile Diagnostic App for Obstructive Sleep Apnea

Autores
Amorim, P; Ferreira-Santos, D; Drummond, M; Rodrigues, PP;

Publicação
DIAGNOSTICS

Abstract
Background/Objectives: Obstructive sleep apnea (OSA) classification relies on polysomnography (PSG) results. Current guidelines recommend the development of clinical prediction algorithms in screening prior to PSG. A recent intuitive and user-friendly tool (OSABayes), based on a Bayesian network model using six clinical variables, has been proposed to quantify the probability of OSA. Our aims are (1) to validate OSABayes prospectively, (2) to build a smartphone app based on the proposed model, and (3) to evaluate app usability. Methods: We prospectively included adult patients suspected of OSA, without suspicion of other sleep disorders, who underwent level I or III diagnostic PSG. Apnea-hypopnea index (AHI) and OSABayes probabilities were obtained and compared using the area under the ROC curve (AUC [95%CI]) for OSA diagnosis (AHI >= 5/h) and higher severity levels (AHI >= 15/h) prediction. We built the OSABayes app on 'App Inventor 2', and the usability was assessed with a cognitive walkthrough method and a general evaluation. Results: 216 subjects were included in the validation cohort, performing PSG levels I (34%) and III (66%). OSABayes presented an AUC of 83.6% [77.3-90.0%] for OSA diagnosis and 76.3% [69.9-82.7%] for moderate/severe OSA prediction, showing good response for both types of PSG. The OSABayes smartphone application allows one to calculate the probability of having OSA and consult information about OSA and the tool. In the usability evaluation, 96% of the proposed tasks were carried out. Conclusions: These results show the good discrimination power of OSABayes and validate its applicability in identifying patients with a high pre-test probability of OSA. The tool is available as an online form and as a smartphone app, allowing a quick and accessible calculation of OSA probability.

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